Stasys Platelet System

The system is designed to form microclots from whole blood samples to measure platelet forces, aggregation, and function.

No use of agonists or reagents, no offsite labs; faster, more accurate results means faster, more-informed decision-making for trauma doctors.

Results in 3 minutes

The Stasys test is rapid and self-contained. Simply attach a whole blood sample syringe to the sensor card, then insert the card into the machine. No pipettes, no mixing, the system reproduces in vivo shear activation conditions within seconds and the test is complete in under 3 minutes giving doctors and clinicians the valuable data they need to make informed decisions, faster.

The System is designed for use at point-of-care and consists of three parts:

Output

The system leverages high precision microfluidics with machine vision, machine learning, and delivers easy to interpret platelet and hemostasis data:

  • Rates of clot formation
  • Rates of clot aggregation
  • Platelet forces
  • Clotting behavior
Part 1

The Machine

Built for use at point-of-care, the machine has a user-friendly interface, consisting of intuitive card-loading and a screen that clearly displays results of the sample. An internal windows-based computer is used for operation. Results of the blood sample are ready within five minutes, empowering doctors and clinicians to make quicker decisions, for better patient outcomes.

Specifications
The system operates on 120 V AC power common to North America and requires a peak of 4A of power during start-up to heat up the card holder.
The program that operates the hardware is written in python 3 and drivers interfacing with the computer are designed with python 3 interfacing in mind.

Part 2

The Card

Function
The single-use microcard, which contains the sensor to assess coagulopathy, ensures that tests can be done easily and efficiently, and with a controlled high-precision injection of blood to be sampled.

Design
The disposable microcard enables clinicians and doctors to obtain accurate results easily–eliminating the need to engage with an offsite lab–with both speed and reliability.

As the sample moves through the card, microclots form and the force of the bond is measured.

An individual sensor at the micron scale within the card, and the shear gradients that it creates on passing streamlines of blood.

Part 3

The Sensor

The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors the blood to assess coagulopathy:

  • Rates of clot formation
  • Rates of clot aggregation
  • Platelet forces
  • Clotting behavior

The card is loaded easily into the benchtop machine, where platelet forces, aggregation, and function are measured rapidly.

Having the ability to measure the critical characteristics of a clot in 5 minutes or less could make the difference between life and death in major trauma patients.

Dr. John Holcomb

Trauma surgeon and former trauma consultant for the U.S. Army

How Stasys is helping trauma doctors

Get an individualized anti-clotting response
Measure the dose response to different common platelet inhibitors and anticoagulants including Aspirin, Heparin, and Plavix (clopidogrel).

Ease to use
The benchtop machine allows trauma doctors to test blood at the point of care without the need to mix in activators.